Domenico Ghirlandaio died on 11 January 1494 in Florence. He was about 45 years old. Domenico led one of the busiest workshops in late fifteenth-century Florence, producing portraits, altarpieces, and narrative frescoes for the city’s leading patrons. Though Vasari characterized him as unconcerned with financial affairs, documents reveal that he was a shrewd businessman with considerable material wealth and property. His brothers Davide and Benedetto and son Ridolfo were active as painters in Florence through the middle of the 16th century.
Reference: Jean K. Cadogan and Andrea Muzzi. “Ghirlandaio.” Grove Art Online. Oxford Art Online. Oxford University Press, http://www.oxfordartonline.com/subscriber/article/grove/art/T031960pg1.
Portrait of an Old Man and a Boy, oil on panel, c. 1485, Paris, Musée du Louvre; photo credit: Erich Lessing/Art Resource, NY
Francesco Sassetti (1421–1490) and His Son Teodoro, ca. 1488, tempera on panel, The Metropolitan Museum of Art, New York, The Jules Bache Collection, 1949
Confirmation of the Rule, 1483-85, fresco, Sassetti Chapel, Santa Trinità, Florence
St. Jerome in his Study,1480, fresco, Ognissanti, Florence
Birth of the Virgin, fresco from the Life of the Virgin cycle, 1486–90, Tornabuoni chapel, Santa Maria Novella, Florence; photo credit: Scala/Art Resource, NY
Last Supper, c. 1486, fresco, San Marco, Florence